Polynucleotide
Polynucleotide treatments, sometimes called polynucleotide therapy
Polynucleotide treatments, sometimes called polynucleotide therapy, are an innovative approach in regenerative medicine and dermatology aimed at rejuvenating and repairing skin tissues. Polynucleotides are long chains of nucleotides (the building blocks of DNA and RNA) and serve as a biocompatible, natural component that can promote cell growth, repair damaged tissues, and reduce inflammation.
Mechanism of Polynucleotide Treatments
Tissue Repair and Regeneration
Polynucleotides stimulate fibroblasts (cells responsible for producing collagen) in the skin. This promotes tissue repair, particularly beneficial for skin damaged by UV rays, pollution, or age.
Hydration and Elasticity
Polynucleotides help bind water in the skin, enhancing hydration and elasticity. This is particularly useful for addressing fine lines and wrinkles.
Anti-inflammatory Effects
Polynucleotides have a natural anti-inflammatory effect, which can help soothe and calm irritated or inflamed skin, often seen in conditions like rosacea or after treatments that stress the skin.
Cell Proliferation and Angiogenesis
They promote cell proliferation and new blood vessel formation (angiogenesis), improving overall skin tone, texture, and health.
Applications in Dermatology
Skin Rejuvenation: Polynucleotide treatments can reduce the appearance of fine lines, wrinkles, and age spots by promoting collagen and elastin production.
Scarring: They can be used to treat acne scars or surgical scars by promoting tissue regeneration.
Wound Healing: Polynucleotides are also used in wound care as they help accelerate the healing process.
Hair Loss: Some studies have explored polynucleotide injections to support scalp health and potentially stimulate hair growth.
Procedure
Polynucleotides are commonly injected into the dermis or applied topically with microneedling to ensure penetration into the skin. Sessions are usually done in a series, spaced a few weeks apart, to allow cumulative benefits.
Safety and Side Effects
Because they are derived from salmon DNA (chosen for its high compatibility with human skin and minimal allergenic properties), polynucleotide treatments are generally considered safe and biocompatible.
Side effects are typically mild, limited to slight redness or swelling at the injection site.
Benefits Compared to Other Treatments
Polynucleotide treatments are often considered gentler than some synthetic options, offering natural skin rejuvenation without harsh chemicals. They’re a good alternative for those looking for a more natural or minimally invasive approach.
Polynucleotide therapy is becoming a popular option for non-surgical aesthetic treatments, providing a balance between efficacy and safety, especially in skin rejuvenation and repair.
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